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Comparison of Hemoglobins from Various Subjects Living in Hypoxia

Scientific Journals of Bogor Agricultural University

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Title Comparison of Hemoglobins from Various Subjects Living in Hypoxia
 
Creator PUSPITANINGRUM, RINI; Department of Biology, Faculty of Mathematics and Natural Sciences, State University of Jakarta
MANTOLINI, KURNIA NUZTIR; Department of Biology, Faculty of Mathematics and Natural Sciences, State University of Jakarta
RUSDI, .; Department of Biology, Faculty of Mathematics and Natural Sciences, State University of Jakarta
SADIKIN, MOHAMAD; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Indonesia
 
Subject biology
Monopterus albus; Clarias bathracus; Hyposarcus pardalis; Chelonia mydas; human umbilical cord; Thalassemia Patient and Human adult; haemoglobin protein content
biology
 
Description The aim of this research was to obtain the different characteristics of haemoglobin molecules in subjects under hypoxic condition, namely eel, catfish, suckermouth fish, green sea turtle using an electrophoresis technique. We used human umbilical cord blood and thalassemia patient blood, as well as a normal adult-human blood as controls. The proteins obtained after electrophoresis process were stained with two different colouring techniques, each based on different principles. Both staining techniques gave practically identical results. Subject that live in hypoxic condition has a different haemoglobin in comparison to the one found in adult human live in normal oxygen condition (normoxia). These hypoxia-adapted or -needed hemoglobin migrate slower than adult human hemoglobin from normoxia. This observation suggests that hemoglobin which is needed to live in hypoxic condition or environment is a different molecule. Whether this hemoglobin from hypoxic condition has a higher affinity to oxygen is not yet known. 
 
Publisher Bogor Agricultural University, Indonesia
 
Contributor
 
Date 2013-09-30
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://journal.ipb.ac.id/index.php/hayati/article/view/6861
 
Source HAYATI Journal of Biosciences; Vol 20, No 3 (2013): September 2013; 99
2086-4094
1978-3019
 
Language eng
 
Relation http://journal.ipb.ac.id/index.php/hayati/article/view/6861/5480